awakeningfromalzheimers Day 2 https://regainyourbrain.awakeningfromalzheimers.com/new-episode Dr Dale Bredesen (San Francisco, CA): The “Silver Buckshot” Protocol: Identifying and Reversing the 3 Primary Forms of Dementia book: The End of Alz (pub in 2014) 1st person to have documented how he reversed alz, and continues to do so in 9 of 10 people book explaines how he did it alz is 3 separate syndroms a personalized protocol MCI or SCI (pre-alz) 20th century: what is the diagnosis? heart failure, alz, cancer 21st century: why did you get this dissease, cardio vascular disease, alz, cancer (the 3 major leading causes of death) - complicated, many many diff things that contribute to cognitive decline - 3 types of alz - amaloyd is brain's protective response to 3 types of pathogens and insults - - type 1 alz: inflamitory, e.g.. from foods you eat: trans fats, sugars cause inflamation, and... - - - inflamation from chronic pathogens: herpies simplex virus type 1, lyme disease, borelia, other tick born illnessses specific fungi and molds, molds, bacteria (gengivitus in your mouth) poor diet, amaloyd is a response because ongoing inflamaatory state expecting pathogens, e.g., leaky gut related to arthritus, cardio vascular diseast, chronic inflamation related to cognitive decline plaques are a barrier to microbes coming from inflamation, everyone over 40 yrs old has some amount, like having cholesterol, may have more or less but not something you don't have, so it's a question of how much, are you continuing inflamation and continuing downsizing, or does it plateau typical person w/type 1 symptoms is in 60's, 70's for type 2 and in 50's for type 3 know it's type 1 from computer algorythm that looks at 150 diff parameters and gives %age of 1,2,3 - can tell type 1 based on inflalmatory profile, e.g., high HSCRP (high sensitivity C reactive protine, which s/b less than 1.0 [having 10.0 w/b outrageous!]), interlukin-6, tuminacrosis factor alpha how to get better: had senior moments, difficulty at work, rememberfing appointments, alz in famile, had scans that indicated alz, went on program, after 3 months improved, after 3 yrs, doing well; had had a horrible life style; while on program does well, but, when off program - declines again - so - back on to program... SILVER BUCKSHOT: processed foods, GMO foods, SAD (std am. diet - leads to alz) - everyone over 50 should have a colonoscpy, everyone over 45 should have a cognoscopy to find out blood testing for genetics and bio chemistry, find out if have chronic infections, where stan genetically, where stand with performance - alz s/b a rare disease - program to come back takes 3 to 6 months to awaken - - type 2 alz: atrophic, i.e., cannot add new memories; withdrawal of trophic supporting infliuences on your brain, e.g., vit-d, estrovial, tesosterone, nerve growth factor, brain derived neuro groth factor (BDNF), vit-b12, other nutrients from not being able to support the network structure in the brain, 10xx15th synapses in brain, start downsizing if can't support new stuff, i.e., short term memory in order to keep older learned things trophic is life supporting to allow functioning and survival hormones have a trophic affect, vit-d too much sugar, chronically high insulin, develop insulin resistance, inflamation from high sugar tood can lead to type 1 and to type 2 type 2 if low thyroid, low vit-d, early historectomy (including ovaris) 50% risk increase not all that inflamation but decrease in cognition and synaptic network short term memroy loss, usually 70's, can be 60's or 50's brain fog from rapid drop in hormonal support in the brain other memory stuff still works (driving, checkbook, etc), just cant learn or remember new things - - type 1.5 alz, a suger related problem and are pre-diabetic ahd get insulin resistance you get both inflamation and atrophic withdrawal - - type 3 alz: toxic alz, exposed to specific toxins, e.g., chemical toxins, e.g., mercury, copper, or, mico-toxins - mold related toxins lewie body dementia similar to type 3, people typically start young 40's to 50's can't follow diections, organixing, visual perception calculating (figure a tip at dinner), depression (and treatment for depression wont fix, in fact just delay's diagnosis) all have some sort of toxic exposure most common are mold that produce neuro toxins, not an inflamation happening there, lyme disease mercury as in seafood ddt, aluminum type 1 & 2 show up in hipocampus, type 3 throughout the brain mold: if a chile, may get asthma, parent fibromyalgia other parent might get cognitive decline looks like a have one type of exposure lowers resistance to other types also ERMI test (env protec agency mold test), as glutothyon level increases, do better, exercise gets better - - GENETIC DISPOSITION apoee(sp) gene 325million americans, 1/4, 75mill are apoe-4 positive w/single copy so risk is 30%, no copy risk is 9%, 7mill w/2 copies and their risk is over 50% find out status and get on prevention early typically get type 1 or 2 or 1.5; if apoe-4 positive usually not type 3 aope-4 makes cells more inflamatory, not good as getting older - what to do - - 1: look at book, why various tests - - 2: mpicognition.com or drbredeson.com - - 3: talk to doc aware of this program, find one on website meet w/doc to get a personalized program to follow - - do the "recode protocol" - - if you're a doctor and not doing nutrition then not working in 21st century - - programatics: programs for people to follow brain is important to take care of - recommend everyone, esp if family history of alz or dimentia or some suggestion of some decline over 45, have cognoscopy look at function, there is online tools (most are inexpensive), amoca score is free, do it in 15 minutes blood tests and docs trained in this can tell you where you are in 1,1.5,2,3, systemic inflamation, glycotoxicity, fasting insulin, trophic support genetis to type 3 for micro toxins - types 1 & 2 typically start w/memory loss, type 3 starts w/executive disfunction, e.g., planning, calculation, visual perception, word finding - plaque is created as a protection, so, removing plaque can make a person worse, must look at cause of why plaque was created - fix that KF!